Although brewing yeasts have strong vitality and strong cell walls, which can make them survive in an acidic environment with alcohol, but this doesn’t mean that they won’t die, especially in the fermentation environment with long beer storage time and strong survival pressure.
When the yeast dies, yeast autolysis releases some unpleasant flavors into the beer. Also a lot amount of yeast deposits can lead to unpleasant mouthfeel and imperfections.